at the National Center for
Emergency Medicine Informatics
Mark Smith, MD
Jon Handler, MD
Mike Gillam, MD
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Emergency Medicine Resources at the National Center for Emergency Medicine Informatics |
Craig Feied, MD Mark Smith, MD Jon Handler, MD Mike Gillam, MD |
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Emergency Medicine Resources at the National Center for Emergency Medicine Informatics -- offering clinical calculators, tools, and reference materials for clinical emergency medicine, medical education, medical research, and ER management, as well as many other emergency medicine resources. What is the Calculator for Indications and Contraindications to tPA In Acute Stroke?The NINDS trial from the NIH found that some stroke patients can benefit greatly from fibrinolysis (thrombolysis) with tissue plasminogen activator (tPA). The patients who improved significantly were those who received thrombolysis with tPA within 3 hours of the initial onset of symptoms. Not every patient is a good candidate for this treatment, and the study included numerous important indications and contraindications. To help emergency physicians decide quickly whether a patient with an acute stroke should be given tPA, we created this checklist that shows all the indications and contraindications in a format useful for emergency medicine. This tool calculates a score that tells whether tPA is indicated, possibly indicated, or contraindicated in a given situation. Go forward to this tool or section Go to the NCEMI home page |
Copyright 1998 by Jonathan A. Handler, MD, Craig F. Feied, MD, and NCEMI |